Collecting New X-Men (2004) #16-32. A bold new direction for the Xavier Institute! In the mutant-controlled _ouse of M_reality, the New Mutants clash with S.H.I.E.L.D._ Hellions over the fate of the human resistance. But when the real world is restored, almost all of Earth_ mutants find themselves depowered! With their species all but gone and emboldened enemies looming on all sides, the remaining New X-Men close ranks and form a new squad _but what about their suddenly human friends and classmates? And what happens when X-23 arrives at the mansion? The rules have changed, the safeties are off _and Reverend Stryker has found a terrifying new weapon in his holy crusade against mutants! The New X-Men will be battered, beaten and worse, and suffer assaults on all fronts. Can this untested new team summon the strength to survive and triumph?